Delaware Center for Musculoskeletal Research
The Delaware Center for Musculoskeletal Research (DCMR) supports basic and preclinical research on the central theme of musculoskeletal health—from the level of the joints to the actions of key cells and molecules—with emphasis on understanding the mechanisms by which physical and biological cues influence tissue structure and normal function and dysfunction, and identifying potential therapeutic interventions.
We aim to:
- Accelerate fundamental musculoskeletal research by supporting synergistic and multidisciplinary research projects.
- Galvanize capabilities for musculoskeletal research by establishing a Multiscale Assessments Research Core.
- Amplify the impact of musculoskeletal research through faculty mentoring, expansion, and retention.
Research
Accelerating Fundamental Musculoskeletal Discoveries
Translating Fundamental Discoveries to the Clinic
Musculoskeletal Research Symposium
You’re invited to attend the Research Symposium co-sponsored by the Delaware Center for Musculoskeletal Research (DCMR) and the Center for Biomechanical Engineering Research (CBER)
Friday, April 26, 2024
UD STAR North Atrium
8:45 a.m. – Welcome
9 a.m. – Keynote Lecture: Karl Lewis (Cornell University) “Fluorescent imaging advances for the study of osteocyte mechanotransduction mechanisms”
10 a.m. – Faculty Talk: Chris Price (DCMR)
10:15 a.m. – Podium Session 1
11:15 a.m. – Poster Pitch
Noon – Lunch
12:45 p.m. – Poster Session 1
1:30 p.m. – Poster Session 2
2:15 p.m. – Podium Session 2
3:15 p.m. – Faculty Talk: Liyun Wang (CBER)
3:30 p.m. – Awards and Adjourn
Keynote abstract
Karl Lewis
Fluorescent imaging advances for the study of osteocyte mechano-transduction mechanisms.
Prof. Lewis studies the interplay of mechanical inputs and biological outcomes in bone. In service of this goal, he develops novel intravital imaging techniques for studying osteocyte mechanotransduction and mechanobiology in vivo. These approaches leverage fluorescent signals to observe cellular/molecular level events and allow for experiments that keep critical endocrine and tissue crosstalk pathways intact. As such, they offer powerful insights into cellular behavior in health and disease. In this presentation, Prof. Lewis will share new approaches and subsequent findings related to osteocyte mechanoregulation and endocytosis. Dr. Karl Lewis is an assistant professor in the Meinig School of Biomedical Engineering at Cornell University.
Course Offering:
BMEG867 – Research techniques for preclinical analysis in rodents
Grading: P/F
Instructors: Gwen Talham, Christine Stinger, Millicent Sullivan
Instructor permission required
This course provides hands-on instruction to prepare student researchers to design and perform experiments involving rodent handling and rodent surgery. Key topics include ethics, regulatory considerations, animal protocol design and execution, and drug/medical device approval.
Events
4/11/24 DCMR Lunch-and-Learn Seminar
FREE Lunch will be provided. RSVP Here! Registration closes today! https://forms.gle/nXGS4UfzGrdeTvU89 The DCMR Research Core is excited to host a seminar featuring short talks by researchers who have used the DCMR Research Core to answer their research questions. ...
4/5/24 BME Seminar “Probing Collagen Molecular Damage in Connective Tissues”
3/18/24 BISC Seminar “Interstitial Muscle Cells in Regenerative and Pathologic Bone Formation”
3/18/24 Axe Family Distinguished Honors Alumni Lecture
News
Faculty Spotlight: Velia Fowler
ARCHITECTURE OF CELLS Article by Hilary Douwes Photos by Evan Krape | Photo illustration by Jeffrey C. Chase February 29, 2024 Velia Fowler’s UD lab studies how cell structure can lead to health issues Click here to read the UDaily article.
Professor Position in Mechanical Engineering
Faculty Spotlight: Emily Day
Thanks to an R35 grant from the National Institutes of Health (NIH), associate professor Emily Day and her research group will continue their innovative research on designing, characterizing and using unique nanoparticles to manage disease Click here for UDaily...
Key to Preventing Osteoarthritis
Click here for UDaily article